Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0X3LD
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| Former ID |
DIB005598
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| Drug Name |
Valtorcitabine
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| Synonyms |
Epcitabine; Torcitabine; LDC-300; NV-02C; L-2-deoxycytidine; Val-L-dC; Beta-L-2`-deoxycytidine; L-dC prodrug, Idenix/Novartis; L-dC, Idenix/Novartis
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| Drug Type |
Small molecular drug
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| Indication | Hepatitis virus infection [ICD-11: 1E50-1E51; ICD-9: 573.3] | Discontinued in Phase 2 | [1] | |
| Company |
Idenix Pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H22N4O5
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| Canonical SMILES |
CC(C)C(C(=O)OC1CC(OC1CO)N2C=CC(=NC2=O)N)N
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| InChI |
1S/C14H22N4O5/c1-7(2)12(16)13(20)23-8-5-11(22-9(8)6-19)18-4-3-10(15)17-14(18)21/h3-4,7-9,11-12,19H,5-6,16H2,1-2H3,(H2,15,17,21)/t8-,9+,11+,12+/m1/s1
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| InChIKey |
VFCYZPOEGWLYRM-QCZKYFFMSA-N
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| CAS Number |
CAS 380886-95-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis B virus Polymerase (HBV P) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800013710) | |||
| REF 2 | Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting. J Pharm Sci. 2008 Mar;97(3):1109-34. | |||
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