Drug Information
Drug General Information | Top | |||
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Drug ID |
D0WW1K
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Former ID |
DNC000044
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Drug Name |
2-(4-hydroxylphenyl)-3-(3,5-dihydroxylphenyl) propenoic acid (NNU-hdpa)
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Synonyms |
ZINC34018202; (E)-alpha-(4-Hydroxyphenyl)-3,5-dihydroxycinnamic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
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Download2D MOL |
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Formula |
C15H12O5
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Canonical SMILES |
C1=CC(=CC=C1C(=CC2=CC(=CC(=C2)O)O)C(=O)O)O
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InChI |
1S/C15H12O5/c16-11-3-1-10(2-4-11)14(15(19)20)7-9-5-12(17)8-13(18)6-9/h1-8,16-18H,(H,19,20)/b14-7+
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InChIKey |
LGVSCQYCQUYTOK-VGOFMYFVSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Inhibitor | [1] |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | Anti-inflammatory effects and gastrointestinal safety of NNU-hdpa, a novel dual COX/5-LOX inhibitor. Eur J Pharmacol. 2009 Jun 2;611(1-3):100-6. |
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