Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0W5OM
|
|||
Former ID |
DNC006584
|
|||
Drug Name |
4-tert-butyl-N-o-tolylthiazol-2-amine
|
|||
Synonyms |
CHEMBL382244; 4-tert-butyl-N-o-tolylthiazol-2-amine; BDBM50183109
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C14H18N2S
|
|||
Canonical SMILES |
CC1=CC=CC=C1NC2=NC(=CS2)C(C)(C)C
|
|||
InChI |
1S/C14H18N2S/c1-10-7-5-6-8-11(10)15-13-16-12(9-17-13)14(2,3)4/h5-9H,1-4H3,(H,15,16)
|
|||
InChIKey |
LGKMKCIPKKOAPX-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | C-C chemokine receptor type 4 (CCR4) | Target Info | Inhibitor | [1] |
KEGG Pathway | Cytokine-cytokine receptor interaction | |||
Chemokine signaling pathway | ||||
Viral carcinogenesis | ||||
Panther Pathway | Inflammation mediated by chemokine and cytokine signaling pathway | |||
Reactome | Chemokine receptors bind chemokines | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Peptide GPCRs | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
---|---|---|---|---|
REF 1 | Optimization of 2-aminothiazole derivatives as CCR4 antagonists. Bioorg Med Chem Lett. 2006 May 15;16(10):2800-3. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.