Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W3ON
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| Former ID |
DNC010091
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| Drug Name |
5-aminoquinolin-8-ol
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| Synonyms |
5-aminoquinolin-8-ol; 13207-66-4; 5-Amino-8-hydroxyquinoline; 8-Quinolinol, 5-amino-; 5-Amino-8-quinolinol; 5-Amino-quinolin-8-ol; 5-azanylquinolin-8-ol; YDEUKNRKEYICTH-UHFFFAOYSA-N; AS-0308-225; 5-aminoquinoline-8-ol; AC1L9ASV; 5-Amino-8-quinolinol #; SCHEMBL688655; 5'-amino-8'-hydroxyquinoline; CHEMBL449298; AMOT0046; AC1Q523Z; cid_416002; BDBM32142; CTK0H3311; DTXSID20328975; MolPort-000-000-986; ZINC120515; ALBB-024871; 5-Amino-8-hydroxyquinoline HClsalt; ANW-61190; 5928AA; BBL028356; STK737829; SBB005680; AKOS000111586
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C9H8N2O
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| Canonical SMILES |
C1=CC2=C(C=CC(=C2N=C1)O)N
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| InChI |
1S/C9H8N2O/c10-7-3-4-8(12)9-6(7)2-1-5-11-9/h1-5,12H,10H2
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| InChIKey |
YDEUKNRKEYICTH-UHFFFAOYSA-N
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| CAS Number |
CAS 13207-66-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Indoleamine 2,3-dioxygenase 1 (IDO1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation | ||||
| L-kynurenine degradation | ||||
| Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | ||||
| NAD de novo biosynthesis | ||||
| KEGG Pathway | Tryptophan metabolism | |||
| Metabolic pathways | ||||
| African trypanosomiasis | ||||
| NetPath Pathway | TSLP Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Tryptophan Metabolism | |||
| Reactome | Tryptophan catabolism | |||
| WikiPathways | Tryptophan metabolism | |||
| Metabolism of amino acids and derivatives | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem. 2010 Feb 11;53(3):1172-89. | |||
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