Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0W0FI
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| Former ID |
DNC006450
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| Drug Name |
N'-(phenylsulfonyl)quinoline-6-carbohydrazide
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| Synonyms |
CHEMBL437697; SCHEMBL6235703; YPRPLJAGGWUKMX-UHFFFAOYSA-N; BDBM50172936; N''-(phenylsulfonyl)quinoline-6-carbohydrazide; Quinoline-6-carboxylic acid 2-(phenylsulfonyl)hydrazide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H13N3O3S
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| Canonical SMILES |
C1=CC=C(C=C1)S(=O)(=O)NNC(=O)C2=CC3=C(C=C2)N=CC=C3
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| InChI |
1S/C16H13N3O3S/c20-16(13-8-9-15-12(11-13)5-4-10-17-15)18-19-23(21,22)14-6-2-1-3-7-14/h1-11,19H,(H,18,20)
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| InChIKey |
YPRPLJAGGWUKMX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Branched-chain-amino-acid transaminase 2 (BCAT2) | Target Info | Inhibitor | [1] |
| BioCyc | Leucine degradation | |||
| Valine degradation | ||||
| Isoleucine degradation | ||||
| KEGG Pathway | Valine, leucine and isoleucine degradation | |||
| Valine, leucine and isoleucine biosynthesis | ||||
| Pantothenate and CoA biosynthesis | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| 2-Oxocarboxylic acid metabolism | ||||
| Biosynthesis of amino acids | ||||
| Panther Pathway | Alanine biosynthesis | |||
| Isoleucine biosynthesis | ||||
| Leucine biosynthesis | ||||
| Valine biosynthesis | ||||
| WikiPathways | Metabolism of amino acids and derivatives | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The design and synthesis of human branched-chain amino acid aminotransferase inhibitors for treatment of neurodegenerative diseases. Bioorg Med Chem Lett. 2006 May 1;16(9):2337-40. | |||
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