Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0VT2C
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| Former ID |
DIB000656
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| Drug Name |
FK-505
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| Synonyms |
FR-76505; 2-[3-(4-Bromo-2-fluorobenzyl)-7-fluoro-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl]acetic acid
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| Drug Type |
Small molecular drug
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| Indication | Hyperuricaemia [ICD-11: 5C55.Y] | Phase 2 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C17H11BrF2N2O4
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| Canonical SMILES |
C1=CC2=C(C=C1F)N(C(=O)N(C2=O)CC3=C(C=C(C=C3)Br)F)CC(=O)O
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| InChI |
1S/C17H11BrF2N2O4/c18-10-2-1-9(13(20)5-10)7-22-16(25)12-4-3-11(19)6-14(12)21(17(22)26)8-15(23)24/h1-6H,7-8H2,(H,23,24)
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| InChIKey |
XLOHSVVOWVIPFC-UHFFFAOYSA-N
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| CAS Number |
CAS 112733-08-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | FK506-binding protein (FKBP) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | X-Ray Powder Diffraction Study on the Grinding Effect of the Polymorphs of a Novel and Orally Effective Uricosuric Agent: FR76505. Volume 20, Issue 18, 1994. | |||
| REF 2 | Prevention of Cardiac Hypertrophy by Calcineurin Inhibition. Circulation Research. 1999; 84: 623-632. | |||
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