Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0VR3K
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| Former ID |
DNC014695
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| Drug Name |
4-Amino-3-(4-fluoro-phenyl)-butyric acid
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| Synonyms |
(R)-4-AMINO-3-(4-FLUOROPHENYL)BUTANOIC ACID; 741217-33-4; CHEMBL301492; (3R)-4-amino-3-(4-fluorophenyl)butanoic acid; AK-87533; PubChem18292; SCHEMBL351702; CTK5D9380; KS-00000QGP; DTXSID00557064; MolPort-023-332-505; ZINC6093177; ANW-65813; 1505AC; BDBM50368295; AKOS006325793; LS30154; CA-2040; DS-2490; AC-22391; AJ-55750; TC-154558; AX8236708; KB-210177; ST24020736; (R)-3-(4-Fluorophenyl)-4-aminobutyric acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H12FNO2
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| Canonical SMILES |
C1=CC(=CC=C1C(CC(=O)O)CN)F
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| InChI |
1S/C10H12FNO2/c11-9-3-1-7(2-4-9)8(6-12)5-10(13)14/h1-4,8H,5-6,12H2,(H,13,14)
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| InChIKey |
QWHXHLDNSXLAPX-UHFFFAOYSA-N
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| CAS Number |
CAS 52237-19-1
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| GABAergic synapse | ||||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | Activation of G protein gated Potassium channels | |||
| G alpha (i) signalling events | ||||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
| WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Potassium Channels | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 3-Thienyl- and 3-furylaminobutyric acids. Synthesis and binding GABAB receptor studies. J Med Chem. 1991 Aug;34(8):2557-60. | |||
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