Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0VM5U
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| Former ID |
DNC000834
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| Drug Name |
KJM429
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| Synonyms |
MK-056; CHEMBL228451; thiourea analogue, 1; SCHEMBL1268701; BDBM20315; N-(4-t-butylbenzyl)-N'-[4-(methyl-sulfonylamino)benzyl]thiourea
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C20H27N3O2S2
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| Canonical SMILES |
CC(C)(C)C1=CC=C(C=C1)CNC(=S)NCC2=CC=C(C=C2)NS(=O)(=O)C
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| InChI |
1S/C20H27N3O2S2/c1-20(2,3)17-9-5-15(6-10-17)13-21-19(26)22-14-16-7-11-18(12-8-16)23-27(4,24)25/h5-12,23H,13-14H2,1-4H3,(H2,21,22,26)
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| InChIKey |
LOMAEJPLJSUBML-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| SuperDrug ATC ID |
L01XX32
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| SuperDrug CAS ID |
cas=179324697
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | High affinity antagonists of the vanilloid receptor. Mol Pharmacol. 2002 Oct;62(4):947-56. | |||
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