Drug Information
Drug General Information | Top | |||
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Drug ID |
D0VE7B
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Drug Name |
DSP-2230
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Indication | Neuropathic pain [ICD-11: 8E43.0] | Phase 1 | [1], [2] | |
Company |
Sumitomo Dainippon Pharma
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Structure |
Download2D MOL |
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Formula |
C20H20F3N5O2
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Canonical SMILES |
CC(C(=O)N)NCC1=NC2=C(N1C3CCC3)N=C(C=C2)OC4=CC(=C(C(=C4)F)F)F
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InChI |
1S/C20H20F3N5O2/c1-10(19(24)29)25-9-16-26-15-5-6-17(27-20(15)28(16)11-3-2-4-11)30-12-7-13(21)18(23)14(22)8-12/h5-8,10-11,25H,2-4,9H2,1H3,(H2,24,29)/t10-/m0/s1
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InChIKey |
HHXCJIMPEJSJTG-JTQLQIEISA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated sodium channel alpha Nav1.7 (SCN9A) | Target Info | Inhibitor | [1], [2] |
Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Inhibitor | [1], [2] | |
Reactome | Interaction between L1 and Ankyrins |
References | Top | |||
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REF 1 | Antibodies and venom peptides: new modalities for ion channels. Nat Rev Drug Discov. 2019 May;18(5):339-357. | |||
REF 2 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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