Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0VD5N
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| Former ID |
DNC002714
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| Drug Name |
6-Chloropurine Riboside, 5'-Monophosphate
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| Synonyms |
6-Cl-Purine Ribotide; CHEMBL1683023; 6-Chloropurine riboside 5'-phosphate; 6-Chloropurine riboside 5'-monophosphate; 6-Chloropurine ribotide; AC1L4ML7; AC1Q3SV8; 6-Chloroinosine monophosphate; SCHEMBL622623; 6-chloro-9-(5-o-phosphono-; A-d-ribofuranosyl)-9h-purine; ALOBOMYIOYNCBS-KQYNXXCUSA-N; ZINC13526959; BDBM50222697; A8843; 6-Chloropurine 9-beta-D-ribofuranosyl 5'-monophosphate; 6-Chloro-9-(5-O-phosphono-beta-D-ribofuranosyl)-9H-purine; [(2R,3S,4R,5R)-5-(6-chloropurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen pho
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H13ClN4O7P+
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| Canonical SMILES |
C1=[N+](C2=C(N1)C(=NC=N2)Cl)C3C(C(C(O3)COP(=O)(O)O)O)O
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| InChI |
1S/C10H12ClN4O7P/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(22-10)1-21-23(18,19)20/h2-4,6-7,10,16-17H,1H2,(H2,18,19,20)/p+1/t4-,6-,7-,10-/m1/s1
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| InChIKey |
ALOBOMYIOYNCBS-KQYNXXCUSA-O
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Amidophosphoribosyltransferase (PPAT) | Target Info | Inhibitor | [1] |
| Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] | |
| BioCyc | Purine nucleotides degradation | |||
| Urate biosynthesis/inosine 5'-phosphate degradation | ||||
| Guanosine nucleotides de novo biosynthesis | ||||
| Superpathway of purine nucleotide salvage | ||||
| Purine nucleotides de novo biosynthesis | ||||
| Guanosine ribonucleotides de novo biosynthesis | ||||
| KEGG Pathway | Purine metabolism | |||
| Drug metabolism - other enzymes | ||||
| Metabolic pathways | ||||
| Panther Pathway | De novo purine biosynthesis | |||
| Pathwhiz Pathway | Purine Metabolism | |||
| Reactome | Purine ribonucleoside monophosphate biosynthesis | |||
| WikiPathways | Nucleotide Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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