Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0VB4X
|
|||
| Drug Name |
VTP-43742
|
|||
| Indication | Psoriasis vulgaris [ICD-11: EA90; ICD-9: 696] | Phase 2 | [1] | |
| Autoimmune disease [ICD-11: 4A40-4A45; ICD-9: 279] | Phase 1 | [1] | ||
| Company |
Vitae PharmaceuticalsFort Washington, PA
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C27H35F3N4O3S
|
|||
| Canonical SMILES |
CCS(=O)(=O)C1=CN=C(C=C1)CNC(=O)C2=CC3=C(C(N(C3)CC4CCC(CC4)C(F)(F)F)C(C)C)N=C2
|
|||
| InChI |
1S/C27H35F3N4O3S/c1-4-38(36,37)23-10-9-22(31-14-23)13-33-26(35)19-11-20-16-34(25(17(2)3)24(20)32-12-19)15-18-5-7-21(8-6-18)27(28,29)30/h9-12,14,17-18,21,25H,4-8,13,15-16H2,1-3H3,(H,33,35)/t18?,21?,25-/m1/s1
|
|||
| InChIKey |
XUYMIRYNRKXKOR-JBWFSBJDSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Nuclear receptor ROR-gamma (RORG) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.