Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0VA0J
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| Former ID |
DNC014623
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| Drug Name |
3,4-Dichloro-N-(3,3-diphenyl-allyl)-benzamide
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| Synonyms |
CHEMBL8893; 3,4-Dichloro-N-(3,3-diphenyl-allyl)-benzamide; BDBM50005468
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H17Cl2NO
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| Canonical SMILES |
C1=CC=C(C=C1)C(=CCNC(=O)C2=CC(=C(C=C2)Cl)Cl)C3=CC=CC=C3
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| InChI |
1S/C22H17Cl2NO/c23-20-12-11-18(15-21(20)24)22(26)25-14-13-19(16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-13,15H,14H2,(H,25,26)
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| InChIKey |
OYXWUVAZLKNOAB-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cholecystokinin receptor type A (CCKAR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Insulin secretion | ||||
| Pancreatic secretion | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718. J Med Chem. 1992 Mar 20;35(6):1042-9. | |||
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