Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0V4YO
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| Former ID |
DIB015521
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| Drug Name |
ROCICLOVIR
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| Synonyms |
Hoe-602; Rociclovir; 2-Amino-9-[1,3-bis(isopropoxy)-2-propyloxymethyl]purine; 6-Deoxy-9-(1-isopropoxymethyl-2-isopropoxyethoxymethyl)guanine
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| Drug Type |
Small molecular drug
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| Indication | Virus infection [ICD-11: 1A24-1D9Z] | Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H25N5O3
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| Canonical SMILES |
CC(C)OCC(COC(C)C)OCN1C=NC2=CN=C(N=C21)N
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| InChI |
1S/C15H25N5O3/c1-10(2)21-6-12(7-22-11(3)4)23-9-20-8-18-13-5-17-15(16)19-14(13)20/h5,8,10-12H,6-7,9H2,1-4H3,(H2,16,17,19)
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| InChIKey |
FBHWXSOQXQBXER-UHFFFAOYSA-N
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| CAS Number |
CAS 108436-80-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Herpes simplex virus DNA polymerase UL30 (HSV UL30) | Target Info | Modulator | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001059) | |||
| REF 2 | Herpes simplex virus type 1 DNA polymerase. Mechanism of inhibition by acyclovir triphosphate. J Biol Chem. 1989 May 5;264(13):7405-11. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
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