Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V4TY
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| Former ID |
DNC001072
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| Drug Name |
Oxidized glutathione
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| Drug Type |
Small molecular drug
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| Indication | Breast cancer [ICD-11: 2C60-2C65] | Approved | [1] | |
| Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Investigative | [2] | ||
| Structure |
 |
Download2D MOL
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| Formula |
C20H32N6O12S2
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| Canonical SMILES |
C(CC(=O)NC(CSSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)C(=O)NCC(=O)O)C(C(=O)O)N
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| InChI |
1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1
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| InChIKey |
YPZRWBKMTBYPTK-BJDJZHNGSA-N
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| CAS Number |
CAS 27025-41-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:17858
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutathione reductase (GR) | Target Info | Inhibitor | [3] |
| BioCyc | Glutathione redox reactions II | |||
| Glutathione redox reactions I | ||||
| KEGG Pathway | Glutathione metabolism | |||
| Thyroid hormone synthesis | ||||
| Pathwhiz Pathway | Glutamate Metabolism | |||
| Glutathione Metabolism | ||||
| WikiPathways | Metapathway biotransformation | |||
| Sulfation Biotransformation Reaction | ||||
| Oxidative Stress | ||||
| NRF2 pathway | ||||
| Nuclear Receptors Meta-Pathway | ||||
| Selenium Micronutrient Network | ||||
| Glutathione metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6480-3. | |||
| REF 3 | The purification and properties of glutathione reductase from the cestode Moniezia expansa. Int J Biochem Cell Biol. 1995 Apr;27(4):393-401. | |||
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