Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0V4TY
|
|||
Former ID |
DNC001072
|
|||
Drug Name |
Oxidized glutathione
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Breast cancer [ICD-11: 2C60-2C65] | Approved | [1] | |
Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Investigative | [2] | ||
Structure |
Download2D MOL
|
|||
Formula |
C20H32N6O12S2
|
|||
Canonical SMILES |
C(CC(=O)NC(CSSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N)C(=O)NCC(=O)O)C(C(=O)O)N
|
|||
InChI |
1S/C20H32N6O12S2/c21-9(19(35)36)1-3-13(27)25-11(17(33)23-5-15(29)30)7-39-40-8-12(18(34)24-6-16(31)32)26-14(28)4-2-10(22)20(37)38/h9-12H,1-8,21-22H2,(H,23,33)(H,24,34)(H,25,27)(H,26,28)(H,29,30)(H,31,32)(H,35,36)(H,37,38)/t9-,10-,11-,12-/m0/s1
|
|||
InChIKey |
YPZRWBKMTBYPTK-BJDJZHNGSA-N
|
|||
CAS Number |
CAS 27025-41-8
|
|||
PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:17858
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Glutathione reductase (GR) | Target Info | Inhibitor | [3] |
BioCyc | Glutathione redox reactions II | |||
Glutathione redox reactions I | ||||
KEGG Pathway | Glutathione metabolism | |||
Thyroid hormone synthesis | ||||
Pathwhiz Pathway | Glutamate Metabolism | |||
Glutathione Metabolism | ||||
WikiPathways | Metapathway biotransformation | |||
Sulfation Biotransformation Reaction | ||||
Oxidative Stress | ||||
NRF2 pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Selenium Micronutrient Network | ||||
Glutathione metabolism |
References | Top | |||
---|---|---|---|---|
REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
REF 2 | D-Ala-D-Ala ligases from glycopeptide antibiotic-producing organisms are highly homologous to the enterococcal vancomycin-resistance ligases VanA and VanB. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6480-3. | |||
REF 3 | The purification and properties of glutathione reductase from the cestode Moniezia expansa. Int J Biochem Cell Biol. 1995 Apr;27(4):393-401. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.