Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0V1HK
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| Former ID |
DIB014568
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| Drug Name |
Berlafenone
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| Synonyms |
Bipranol; GK-23G
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| Drug Type |
Small molecular drug
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| Indication | Heart arrhythmia [ICD-11: BC65; ICD-10: I49, I49.8] | Terminated | [1] | |
| Company |
Helopharm
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| Structure |
 |
Download2D MOL |
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| Formula |
C19H25NO2
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| Canonical SMILES |
CC(C)(C)NCC(COC1=CC=CC=C1C2=CC=CC=C2)O
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| InChI |
1S/C19H25NO2/c1-19(2,3)20-13-16(21)14-22-18-12-8-7-11-17(18)15-9-5-4-6-10-15/h4-12,16,20-21H,13-14H2,1-3H3
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| InChIKey |
DBHPVKNFKBKJCE-UHFFFAOYSA-N
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| CAS Number |
CAS 18965-97-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Modulator | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000213) | |||
| REF 2 | WO patent application no. 19990639849, Novel sodium channel drugs and uses. | |||
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