Drug Information
Drug General Information | Top | |||
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Drug ID |
D0V0LA
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Former ID |
DNC014549
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Drug Name |
CGP-35582
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Synonyms |
CGP-35582; CHEMBL113396; SCHEMBL341418; Phosphinic acid, P-(3-amino-1-methylpropyl)-P-methyl-; CCFBFTKQKRGULP-UHFFFAOYSA-N; BDBM50032971; 133345-75-2; P-(4-aminobut-2-yl)-P-methyl-phosphinic acid; (3-Amino-1-methyl-propyl)-methyl-phosphinic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C5H14NO2P
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Canonical SMILES |
CC(CCN)P(=O)(C)O
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InChI |
1S/C5H14NO2P/c1-5(3-4-6)9(2,7)8/h5H,3-4,6H2,1-2H3,(H,7,8)
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InChIKey |
CCFBFTKQKRGULP-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
KEGG Pathway | cAMP signaling pathway | |||
Neuroactive ligand-receptor interaction | ||||
GABAergic synapse | ||||
Estrogen signaling pathway | ||||
Morphine addiction | ||||
Reactome | Activation of G protein gated Potassium channels | |||
G alpha (i) signalling events | ||||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Potassium Channels | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists. J Med Chem. 1995 Aug 18;38(17):3297-312. |
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