Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0U2DY
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| Former ID |
DIB004239
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| Drug Name |
Recombinant TSH superagonists
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| Synonyms |
Recombinant TSH superagonists (thyroid cancer); TR-1401; TR-1402; Recombinant TSH superagonists (thyroid cancer), Trophogen; TSH superagonist (thyroid cancer/goiter), Trophogen; Thyroid stimulating hormone superagonist (thyroid cancer/goiter), Trophogen
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| Indication | Thyroid cancer [ICD-11: 2D10; ICD-10: C73] | Investigative | [1] | |
| Company |
Trophogen Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Thyrotropin receptor (TSHR) | Target Info | Agonist | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Thyroid hormone synthesis | ||||
| Autoimmune thyroid disease | ||||
| NetPath Pathway | Wnt Signaling Pathway | |||
| Pathway Interaction Database | Arf6 trafficking events | |||
| Arf6 signaling events | ||||
| Reactome | Hormone ligand-binding receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | Peptide GPCRs | |||
| TSH signaling pathway | ||||
| Thyroxine (Thyroid Hormone) Production | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 255). | |||
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