Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T8VY
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| Former ID |
DIB002302
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| Drug Name |
Aceclofenac
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| Synonyms |
Airtal; Barracan; Biofenac; Bristaflam; Falcol; Gerbin; Preservex; YT-919
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| Drug Type |
Small molecular drug
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Approved | [1], [2] | |
| Company |
Almirall Prodesfarma SA
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| Structure |
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Download2D MOL |
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| Formula |
C16H13Cl2NO4
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| Canonical SMILES |
C1=CC=C(C(=C1)CC(=O)OCC(=O)O)NC2=C(C=CC=C2Cl)Cl
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| InChI |
1S/C16H13Cl2NO4/c17-11-5-3-6-12(18)16(11)19-13-7-2-1-4-10(13)8-15(22)23-9-14(20)21/h1-7,19H,8-9H2,(H,20,21)
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| InChIKey |
MNIPYSSQXLZQLJ-UHFFFAOYSA-N
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| CAS Number |
CAS 89796-99-6
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:31159
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| ADReCS Drug ID | BADD_D00021 | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Prostaglandin G/H synthase (COX) | Target Info | Modulator | [1], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | ClinicalTrials.gov (NCT01912066) A Multicenter, Double Blinded, Randomized, Parallel Assignment Study to Demonstrate the Efficacy of DA9601. U.S. National Institutes of Health. | |||
| REF 3 | Aceclofenac spares cyclooxygenase 1 as a result of limited but sustained biotransformation to diclofenac. Clin Pharmacol Ther. 2003 Sep;74(3):222-35. | |||
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