Drug Information
Drug General Information | Top | |||
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Drug ID |
D0T6NE
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Drug Name |
Z 944
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Synonyms |
Z-944
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C19H27ClFN3O2
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Canonical SMILES |
CC(C)(C)NC(=O)CN1CCC(CC1)CNC(=O)C2=CC(=CC(=C2)Cl)F
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InChI |
1S/C19H27ClFN3O2/c1-19(2,3)23-17(25)12-24-6-4-13(5-7-24)11-22-18(26)14-8-15(20)10-16(21)9-14/h8-10,13H,4-7,11-12H2,1-3H3,(H,22,26)(H,23,25)
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InChIKey |
JOCLITFYIMJMNK-UHFFFAOYSA-N
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CAS Number |
CAS 1199236-64-0
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Voltage-gated calcium channel alpha Cav3.2 (CACNA1H) | Target Info | Modulator | [1] |
KEGG Pathway | MAPK signaling pathway | |||
Calcium signaling pathway | ||||
Circadian entrainment | ||||
Pathwhiz Pathway | Muscle/Heart Contraction | |||
Reactome | NCAM1 interactions | |||
WikiPathways | Corticotropin-releasing hormone | |||
NCAM signaling for neurite out-growth |
References | Top | |||
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REF 1 | Z944, a Novel Selective T-Type Calcium Channel Antagonist Delays the Progression of Seizures in the Amygdala Kindling Model.PLoS One.2015 Aug 14;10(8):e0130012. |
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