Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T4WL
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| Former ID |
DNC013586
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| Drug Name |
1-hydroxy-3-phenylurea
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| Synonyms |
1-hydroxy-3-phenylurea; Urea, N-hydroxy-N'-phenyl-; Urea, 1-hydroxy-3-phenyl-; 7335-35-5; CHEMBL125955; NSC52953; NSC 52953; WLN: QMVMR; AI3-63229; AC1Q5NHR; SCHEMBL676383; AC1L322W; DTXSID20223597; MolPort-003-699-942; ZINC161805; BDBM50377106; NSC-52953; AKOS024336836
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C7H8N2O2
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| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)NO
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| InChI |
1S/C7H8N2O2/c10-7(9-11)8-6-4-2-1-3-5-6/h1-5,11H,(H2,8,9,10)
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| InChIKey |
AAVSQBMWOCNSDL-UHFFFAOYSA-N
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| CAS Number |
CAS 7335-35-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Analogues of N-hydroxy-N'-phenylthiourea and N-hydroxy-N'-phenylurea as inhibitors of tyrosinase and melanin formation. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3607-10. | |||
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