Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T4SV
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| Drug Name |
US9216972, 132
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| Synonyms |
SCHEMBL1807765; CHEMBL3909064; XVGCLGONKUIZED-UHFFFAOYSA-N; BDBM197672; US9216972, 132; N-(1-cyanocyclopropyl)-2-hydroxy-2-(3-(5-phenyl-4-(trifluoromethyl)isoxazol-3-yl)-4,5-dihydronaphtho[1,2-c]isoxazol-7-yl)acetamide
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C27H19F3N4O4
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| Canonical SMILES |
C1CC2=C(ON=C2C3=C1C=C(C=C3)C(C(=O)NC4(CC4)C#N)O)C5=NOC(=C5C(F)(F)F)C6=CC=CC=C6
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| InChI |
1S/C27H19F3N4O4/c28-27(29,30)19-21(34-37-23(19)14-4-2-1-3-5-14)24-18-9-6-15-12-16(7-8-17(15)20(18)33-38-24)22(35)25(36)32-26(13-31)10-11-26/h1-5,7-8,12,22,35H,6,9-11H2,(H,32,36)
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| InChIKey |
XVGCLGONKUIZED-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target's Patent Info | [1] | |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Tricyclic heterocyclic compounds. US9216972. | |||
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