Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T4FT
|
|||
| Former ID |
DIB019541
|
|||
| Drug Name |
PMID20690647C5a
|
|||
| Synonyms |
Cbz-Leu-D,L-Phe-CONH-(CH(2))(3)-adenin-9-yl; GTPL8615; BDBM50326304
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C32H38N8O5
|
|||
| Canonical SMILES |
CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)C(=O)NCCCN2C=NC3=C(N=CN=C32)N)NC(=O)OCC4=CC=CC=C4
|
|||
| InChI |
1S/C32H38N8O5/c1-21(2)16-25(39-32(44)45-18-23-12-7-4-8-13-23)30(42)38-24(17-22-10-5-3-6-11-22)27(41)31(43)34-14-9-15-40-20-37-26-28(33)35-19-36-29(26)40/h3-8,10-13,19-21,24-25H,9,14-18H2,1-2H3,(H,34,43)(H,38,42)(H,39,44)(H2,33,35,36)/t24?,25-/m0/s1
|
|||
| InChIKey |
OVLNPOAZKHQAAD-BBMPLOMVSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calpain-2 (CAPN2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Protein processing in endoplasmic reticulum | |||
| Apoptosis | ||||
| Alzheimer's disease | ||||
| Reactome | Degradation of the extracellular matrix | |||
| WikiPathways | Focal Adhesion | |||
| Integrated Pancreatic Cancer Pathway | ||||
| Alzheimers Disease | ||||
| Integrin-mediated Cell Adhesion | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors. J Med Chem. 2010 Sep 9;53(17):6326-36. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.