Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T3KK
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| Former ID |
DNC009304
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| Drug Name |
KNI-10093
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| Synonyms |
KNI-10093; CHEMBL452345; BDBM50273723
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C34H39N3O7S
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| Canonical SMILES |
CC1(C(N(CS1)C(=O)C(C(CC2=CC=CC=C2)NC(=O)COC3=CC=CC(=C3)OC)O)C(=O)NC4C(CC5=CC=CC=C45)O)C
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| InChI |
1S/C34H39N3O7S/c1-34(2)31(32(41)36-29-25-15-8-7-12-22(25)17-27(29)38)37(20-45-34)33(42)30(40)26(16-21-10-5-4-6-11-21)35-28(39)19-44-24-14-9-13-23(18-24)43-3/h4-15,18,26-27,29-31,38,40H,16-17,19-20H2,1-3H3,(H,35,39)(H,36,41)/t26-,27+,29-,30-,31+/m0/s1
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| InChIKey |
JUVIZUPSXSIJMO-VFCPCCRCSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Plasmodium Plasmepsin 2 (Malaria PLA2) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin. Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. | |||
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