Drug Information
Drug General Information | Top | |||
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Drug ID |
D0T3CM
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Former ID |
DNC008530
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Drug Name |
BOLINAQUINONE
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Synonyms |
bolinaquinone; SCHEMBL1231059
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C22H30O4
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Canonical SMILES |
CC1C2CCC=C(C2(CCC1(C)CC3=C(C(=O)C=C(C3=O)OC)O)C)C
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InChI |
1S/C22H30O4/c1-13-7-6-8-16-14(2)21(3,9-10-22(13,16)4)12-15-19(24)17(23)11-18(26-5)20(15)25/h7,11,14,16,24H,6,8-10,12H2,1-5H3/t14-,16+,21-,22-/m1/s1
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InChIKey |
PYUXUMSQSVWNDS-NSAJDELNSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Group IIA phospholipase A2 (GIIA sPLA2) | Target Info | Inhibitor | [1] |
Phospholipase A2 (PLA2G1B) | Target Info | Inhibitor | [1] | |
BioCyc | Phospholipases | |||
KEGG Pathway | Glycerophospholipid metabolism | |||
Ether lipid metabolism | ||||
Arachidonic acid metabolism | ||||
Linoleic acid metabolism | ||||
alpha-Linolenic acid metabolism | ||||
Metabolic pathways | ||||
Ras signaling pathway | ||||
Vascular smooth muscle contraction | ||||
Pancreatic secretion | ||||
Fat digestion and absorption | ||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | |||
Glypican 1 network | ||||
Reactome | Acyl chain remodelling of PC | |||
Acyl chain remodelling of PE | ||||
Acyl chain remodelling of PI | ||||
WikiPathways | Glycerophospholipid biosynthesis | |||
Cardiac Hypertrophic Response | ||||
Glycerophospholipid Biosynthetic Pathway | ||||
Spinal Cord Injury | ||||
Eicosanoid Synthesis | ||||
MicroRNAs in cardiomyocyte hypertrophy |
References | Top | |||
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REF 1 | New sesquiterpene derivatives from the sponge Dysidea species with a selective inhibitor profile against human phospholipase A2 and other leukocyte... J Nat Prod. 2001 May;64(5):612-5. |
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