Drug Information
Drug General Information | Top | |||
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Drug ID |
D0T2QN
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Former ID |
DIB010174
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Drug Name |
PF-2393296
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Synonyms |
IDDBCP185108
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Indication | Neuropathic pain [ICD-11: 8E43.0] | Discontinued in Phase 1 | [1] | |
Company |
Pfizer Inc
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor delta (GABRD) | Target Info | Agonist | [2] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027949) | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 416). |
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