Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0T1WY
|
|||
| Former ID |
DCL001173
|
|||
| Drug Name |
Clevudine
|
|||
| Synonyms |
Clevudine; 163252-36-6; Levovir; L-FMAU; UNII-IN51MVP5F1; Clevudine (Levovir); IN51MVP5F1; 1-(2-Deoxy-2-fluoro-beta-L-arabinofuranosyl)thymine; 1-((2S,3R,4S,5S)-3-Fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione; AK106264; 1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]-5-methyl-pyrimidine-2,4-dione; 1-[(2S,3R,4S,5S)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione; Clevudine [USAN:INN]; Revovir; Clevudine (USAN)
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Hepatitis B virus infection [ICD-11: 1E51.0; ICD-10: B18.1] | Phase 3 | [1] | |
| Company |
Bukwang; Eisai
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H13FN2O5
|
|||
| Canonical SMILES |
CC1=CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)F
|
|||
| InChI |
1S/C10H13FN2O5/c1-4-2-13(10(17)12-8(4)16)9-6(11)7(15)5(3-14)18-9/h2,5-7,9,14-15H,3H2,1H3,(H,12,16,17)/t5-,6+,7-,9-/m0/s1
|
|||
| InChIKey |
GBBJCSTXCAQSSJ-XQXXSGGOSA-N
|
|||
| CAS Number |
CAS 163252-36-6
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
619450, 640989, 8195566, 12014935, 14750145, 14750146, 15666039, 43129131, 47205848, 50075841, 57318955, 58106966, 75807091, 92714685, 93302819, 103118595, 103630414, 104354518, 117584619, 124772197, 126629455, 126655265, 126670359, 127928369, 135259744, 137263541, 137267261, 141758521, 143493391, 152090600, 152234295, 160840600, 162201741, 162220958, 163099691, 163405043, 164838487, 172085914, 196109794, 198949300, 223519049, 223660958, 223705195, 223800988, 226585146, 249727250, 250213733, 252055600, 252218289
|
|||
| ChEBI ID |
CHEBI:135964
|
|||
| SuperDrug ATC ID |
J05AF12
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis B virus Reverse transcriptase (HBV RT) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2011 Pipeline of Bukwang. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.