Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0T1CH
|
|||
Former ID |
DNC011101
|
|||
Drug Name |
4-[1-(4'-Methoxybiphenyl-4-yl)propyl]pyridine
|
|||
Synonyms |
CHEMBL1215596; BDBM50324608
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C21H21NO
|
|||
Canonical SMILES |
CCC(C1=CC=C(C=C1)C2=CC=C(C=C2)OC)C3=CC=NC=C3
|
|||
InChI |
1S/C21H21NO/c1-3-21(19-12-14-22-15-13-19)18-6-4-16(5-7-18)17-8-10-20(23-2)11-9-17/h4-15,21H,3H2,1-2H3
|
|||
InChIKey |
DURIQWOMVBEIPW-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Androgen biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
Prolactin signaling pathway | ||||
Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
Steroidogenesis | ||||
Reactome | Androgen biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Endogenous sterols | ||||
WikiPathways | Metapathway biotransformation | |||
Steroid Biosynthesis | ||||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Glucocorticoid & Mineralcorticoid Metabolism | ||||
Prostate Cancer | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
---|---|---|---|---|
REF 1 | Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prosta... J Med Chem. 2010 Aug 12;53(15):5749-58. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.