Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SO5A
|
|||
| Former ID |
DNC013291
|
|||
| Drug Name |
ATC-120
|
|||
| Synonyms |
CHEMBL412885; ATC-120; thiourea analogue, 14; SCHEMBL5947715; BDBM20317; ZINC14973328; BDBM50142759; N-(4-tert-butylbenzyl)-N''-{(1R)-1-[4-(methylsulfonylamino)phenyl]ethyl}thiourea; (R)-N-(4-(1-(3-(4-tert-butylbenzyl)thioureido)ethyl)phenyl)methanesulfonamide; N-(4-{(R)-1-[3-(4-tert-Butyl-benzyl)-thioureido]-ethyl}-phenyl)-methanesulfonamide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H29N3O2S2
|
|||
| Canonical SMILES |
CC(C1=CC=C(C=C1)NS(=O)(=O)C)NC(=S)NCC2=CC=C(C=C2)C(C)(C)C
|
|||
| InChI |
1S/C21H29N3O2S2/c1-15(17-8-12-19(13-9-17)24-28(5,25)26)23-20(27)22-14-16-6-10-18(11-7-16)21(2,3)4/h6-13,15,24H,14H2,1-5H3,(H2,22,23,27)/t15-/m1/s1
|
|||
| InChIKey |
MRGDOZGZFFCDRJ-OAHLLOKOSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Silicon switch approach in TRPV1 antagonist MK-056 and its analogues. Bioorg Med Chem. 2010 Jan 1;18(1):111-6. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.