Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0SE1R
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| Former ID |
DNC014329
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| Drug Name |
4'-(p-Toluenesulfonamide)-4-hydroxychalcone
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| Synonyms |
CHEMBL371723; TSAHC; Sulfonamide chalcone, 4; SCHEMBL3483827; BDBM50174835; 4''-(p-Toluenesulfonamide)-4-hydroxychalcone; 4''-(4-toluenesulfonamido)-4-hydroxychalcone
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C22H19NO4S
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| Canonical SMILES |
CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=C(C=C2)C(=O)C=CC3=CC=C(C=C3)O
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| InChI |
1S/C22H19NO4S/c1-16-2-13-21(14-3-16)28(26,27)23-19-9-7-18(8-10-19)22(25)15-6-17-4-11-20(24)12-5-17/h2-15,23-24H,1H3/b15-6+
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| InChIKey |
KDODYFOOJCIHGK-GIDUJCDVSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Evaluation of anti-pigmentary effect of synthetic sulfonylamino chalcone. Eur J Med Chem. 2010 May;45(5):2010-7. | |||
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