Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S7VN
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| Former ID |
DIB009253
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| Drug Name |
MRL-953
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| Synonyms |
SDZ-MRL-953
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| Indication | Immune System disease [ICD-11: 4A01-4B41; ICD-10: D80-D89] | Terminated | [1] | |
| Company |
Novartis AG
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 1 receptor type 2 (IL1R2) | Target Info | Agonist | [2] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cytokine-cytokine receptor interaction | ||||
| Hematopoietic cell lineage | ||||
| Amoebiasis | ||||
| HTLV-I infection | ||||
| Transcriptional misregulation in cancer | ||||
| NetPath Pathway | IL1 Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Pathway Interaction Database | IL1-mediated signaling events | |||
| Reactome | Interleukin-1 signaling | |||
| WikiPathways | MAPK Signaling Pathway | |||
| Interleukin-1 signaling | ||||
| Apoptosis Modulation and Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002036) | |||
| REF 2 | SDZ MRL 953, a lipid A analog as selective cytokine inducer. Prog Clin Biol Res. 1995;392:549-65. | |||
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