Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0S6GS
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| Former ID |
DNC011775
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| Drug Name |
6-Bromo-2-phenyl-chromen-4-one
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| Synonyms |
6-Bromoflavone; 1218-80-0; 6-bromo-2-phenyl-4H-chromen-4-one; 6-Bromo-2-phenyl-4H-1-benzopyran-4-one; 6-Bromo-2-phenyl-(4H)-4-benzopyranone; 6-bromo-2-phenylchromen-4-one; 6-Bromo-2-phenyl-chromen-4-one; ACMC-20alzx; AC1LAD8N; MLS002473413; CHEMBL52825; SCHEMBL4449962; ZINC58081; DTXSID00332792; HMS3343M11; HMS2224K05; 5956AH; MFCD00276169; AKOS015889624; MCULE-7797339727; ZB002311; ST059081; SMR001397504; KB-247810; TX-017285; 4H-1-Benzopyran-4-one, 6-bromo-2-phenyl-; K-1651; 6-Bromo-2-phenyl-(4H)-4-benzopyranone, 97%
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H9BrO2
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| Canonical SMILES |
C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=CC(=C3)Br
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| InChI |
1S/C15H9BrO2/c16-11-6-7-14-12(8-11)13(17)9-15(18-14)10-4-2-1-3-5-10/h1-9H
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| InChIKey |
LPOZDKMXSPAATL-UHFFFAOYSA-N
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| CAS Number |
CAS 1218-80-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of halogenated/nitrated flavone derivatives and evaluation of their affinity for the central benzodiazepine receptor, Bioorg. Med. Chem. Lett. 7(15):2003-2008 (1997). | |||
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