Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S4XZ
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| Former ID |
DIB011156
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| Drug Name |
GE-1170A
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| Synonyms |
Elongation factor Tu inhibitors (bacterial infection); LDI-028; LDK-733; Elongation factor Tu inhibitors (bacterial infection), Novartis
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| Indication | Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Phase 1 | [1] | |
| Company |
Novartis Institutes for BioMedical Research Inc
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Staphylococcus Elongation factor Tu (Stap-coc tuf) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | GE2270A-resistant mutations in elongation factor Tu allow productive aminoacyl-tRNA binding to EF-Tu.GTP.GE2270A complexes. J Mol Biol. 2000 Dec 15;304(5):995-1005. | |||
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