Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S2TI
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| Former ID |
DIB021251
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| Drug Name |
YM90709
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| Synonyms |
YM-90709; YM 90709
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C22H21N3O2
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| Canonical SMILES |
CC1(CC2=CC(=C(C=C2C3=CC4=NC5=CC=CC=C5N=C4N31)OC)OC)C
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| InChI |
1S/C22H21N3O2/c1-22(2)12-13-9-19(26-3)20(27-4)10-14(13)18-11-17-21(25(18)22)24-16-8-6-5-7-15(16)23-17/h5-11H,12H2,1-4H3
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| InChIKey |
HIXSPVQXXDULHS-UHFFFAOYSA-N
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| CAS Number |
CAS 163769-88-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
1381249, 3938054, 5369638, 9069753, 11114177, 16256002, 42145235, 47700888, 47998959, 53790719, 80557765, 81093354, 85787625, 88976670, 105220798, 110194470, 124579768, 135698090, 162023327, 162799964, 164235799, 165438432, 176226103, 178101783, 179337262, 184587847, 223468955, 223533201, 241182620, 242168157, 248989550
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| ChEBI ID |
CHEBI:92125
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 5 receptor alpha (IL5RA) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5090). | |||
| REF 2 | Characterization of YM-90709 as a novel antagonist which inhibits the binding of interleukin-5 to interleukin-5 receptor. Int Immunopharmacol. 2002 Nov;2(12):1693-702. | |||
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