Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0S2IQ
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| Former ID |
DNAP001441
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| Drug Name |
Sapropterin hydrochloride
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| Synonyms |
Biopten (TN)
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| Drug Type |
Small molecular drug
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| Indication | Hyperphenylalaninemia [ICD-11: 5C50] | Approved | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C9H17Cl2N5O3
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| Canonical SMILES |
CC(C(C1CNC2=C(N1)C(=O)NC(=N2)N)O)O.Cl.Cl
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| InChI |
1S/C9H15N5O3.2ClH/c1-3(15)6(16)4-2-11-7-5(12-4)8(17)14-9(10)13-7;;/h3-4,6,12,15-16H,2H2,1H3,(H4,10,11,13,14,17);2*1H/t3-,4+,6-;;/m0../s1
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| InChIKey |
RKSUYBCOVNCALL-NTVURLEBSA-N
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| CAS Number |
CAS 69056-38-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3153183, 7848860, 11601506, 12014491, 14776738, 14801109, 24277922, 43758872, 56311539, 57407191, 75487273, 91722512, 93581336, 103771501, 113523785, 126685033, 135131482, 137249803, 144205335, 160820722, 162249508, 163091204, 163379274, 164340397, 164827597, 175268612, 223678991, 226607428, 241121735, 250210464, 252237154, 252425064
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| ChEBI ID |
CHEBI:32120
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| SuperDrug ATC ID |
A16AX07
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phenylalanine hydroxylase (PAH) | Target Info | Modulator | [1] |
| BioCyc | Phenylalanine degradation/tyrosine biosynthesis | |||
| KEGG Pathway | Phenylalanine metabolism | |||
| Phenylalanine, tyrosine and tryptophan biosynthesis | ||||
| Metabolic pathways | ||||
| Biosynthesis of amino acids | ||||
| Pathwhiz Pathway | Phenylalanine and Tyrosine Metabolism | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Biogenic Amine Synthesis | ||||
| Metabolism of amino acids and derivatives | ||||
| Abnormal metabolism in phenylketonuria | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2007 FDA drug approvals: a year of flux. Nat Rev Drug Discov. 2008 Feb;7(2):107-9. | |||
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