Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0S0MC
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| Drug Name |
US8524917, 10
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| Synonyms |
SCHEMBL291250; CHEMBL3651713; HYKLZEZGHJEJET-UHFFFAOYSA-N; BDBM101037; US8524917, 10; US8563594, 168; 1-benzyl-N-(3,4-difluorobenzyl)-6-ethoxy-2-isopropyl-1H-indole-3-carboxamide
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C28H28F2N2O2
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| Canonical SMILES |
CCOC1=CC2=C(C=C1)C(=C(N2CC3=CC=CC=C3)C(C)C)C(=O)NCC4=CC(=C(C=C4)F)F
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| InChI |
1S/C28H28F2N2O2/c1-4-34-21-11-12-22-25(15-21)32(17-19-8-6-5-7-9-19)27(18(2)3)26(22)28(33)31-16-20-10-13-23(29)24(30)14-20/h5-15,18H,4,16-17H2,1-3H3,(H,31,33)
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| InChIKey |
HYKLZEZGHJEJET-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine-1-phosphate receptor 3 (S1PR3) | Target's Patent Info | [1] | |
| KEGG Pathway | Sphingolipid signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Pathway Interaction Database | S1P3 pathway | |||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| Reactome | G alpha (i) signalling events | |||
| Lysosphingolipid and LPA receptors | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Small Ligand GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | 6-substituted indole-3-carboxylic acid amide compounds having sphingosine-1-phosphate (S1P) receptor antagonist biological activity. US8524917. | |||
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