Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0S0AS
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| Former ID |
DAP001112
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| Drug Name |
Ipratropium
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| Synonyms |
Aerodose; Atrovent; Atrovent Hfa; Ipatropium Bromide; Ipratropium bromide; X8M; Apo-Ipravent; Apovent (TN); Atrovent (TN); Kendral-Ipratropium; [(5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate; [(1R,5R)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate; [(1R,5S)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] 3-hydroxy-2-phenylpropanoate; [(1R,5S)-8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl] (2R)-3-hydroxy-2-phenylpropanoate; (3-endo,8-syn)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo(3.2.1)octane; (3-endo,8-syn)-3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-isopropyl-8-methyl-8-azoniabicyclo[3.2.1]octane; (8-methyl-8-propan-2-yl-8-azoniabicyclo[3.2.1]octan-3-yl) 3-hydroxy-2-phenylpropanoate; 3-[(3-hydroxy-2-phenylpropanoyl)oxy]-8-methyl-8-(propan-2-yl)-8-azoniabicyclo[3.2.1]octane
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| Drug Type |
Small molecular drug
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| Indication | Obstructive lung disease [ICD-11: CA22.Z] | Approved | [1], [2] | |
| Therapeutic Class |
Bronchodilator Agents
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H30NO3+
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| Canonical SMILES |
CC(C)[N+]1(C2CCC1CC(C2)OC(=O)C(CO)C3=CC=CC=C3)C
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| InChI |
1S/C20H30NO3/c1-14(2)21(3)16-9-10-17(21)12-18(11-16)24-20(23)19(13-22)15-7-5-4-6-8-15/h4-8,14,16-19,22H,9-13H2,1-3H3/q+1/t16-,17+,18?,19?,21?
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| InChIKey |
OEXHQOGQTVQTAT-BZQJJPTISA-N
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| CAS Number |
CAS 60205-81-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
5243543, 5243557, 6951281, 8152369, 11466603, 11467723, 11486345, 26756583, 29222866, 47509536, 50070857, 79331559, 85209499, 85788108, 103127404, 104170067, 104304400, 117575154, 121362439, 124886805, 124968912, 126407694, 128799107, 135650410, 136350344, 136959634, 140035998, 141999271, 142186678, 142719345, 160857166, 162879438, 166233201, 172080692, 176484704, 179148622, 179694577, 226395381, 237172531, 239293942, 242128594, 244502426, 246151890, 248499359
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| ChEBI ID |
CHEBI:5956
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| ADReCS Drug ID | BADD_D01191 ; BADD_D01192 ; BADD_D01193 | |||
| SuperDrug ATC ID |
R01AX03; R03BB01
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| SuperDrug CAS ID |
cas=022254246
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 325). | |||
| REF 2 | Emerging drugs for postoperative ileus. Expert Opin Emerg Drugs. 2007 Nov;12(4):619-26. | |||
| REF 3 | Role of parasympathetic nerves and muscarinic receptors in allergy and asthma.Chem Immunol Allergy.2012;98:48-69. | |||
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