Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0RX2U
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| Drug Name |
PMID25522065-Compound-25
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| Drug Type |
Small molecular drug
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| Company |
GLAXOSMITHKLINE LLC QIN, Donghui CHRISTENSEN, IV, Siegfried Benjamin WU, Chengde ZHANG, Zhiliu YU, Haiyu YUAN, Jiangxing LIN, Xiaojuan XU, Shanli LV, Maoyun YAO, Chen LI, Lei HUANG, Xing GAO, Min
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| Structure |
 |
Download2D MOL |
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| Formula |
C28H32ClN3O2
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| Canonical SMILES |
CC(C)NCCNCC1=CC2=C(C=C1)C=C(CC2)N3C=CC(=CC3=O)OCC4=CC=C(C=C4)Cl
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| InChI |
1S/C28H32ClN3O2/c1-20(2)31-13-12-30-18-22-3-6-24-16-26(10-7-23(24)15-22)32-14-11-27(17-28(32)33)34-19-21-4-8-25(29)9-5-21/h3-6,8-9,11,14-17,20,30-31H,7,10,12-13,18-19H2,1-2H3
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| InChIKey |
SCTPFHKOHPCDLG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
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