Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0RG4J
|
|||
| Drug Name |
Chlorobenzamide derivative 1
|
|||
| Synonyms |
PMID27724045-Compound-26
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Company |
H. LUNDBECK A/S
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C20H17ClF6N2O
|
|||
| Canonical SMILES |
C1CC1(CC(CNC(=O)C2=CC=CC=C2Cl)C3=CN=C(C=C3)C(F)(F)F)C(F)(F)F
|
|||
| InChI |
1S/C20H17ClF6N2O/c21-15-4-2-1-3-14(15)17(30)29-11-13(9-18(7-8-18)20(25,26)27)12-5-6-16(28-10-12)19(22,23)24/h1-6,10,13H,7-9,11H2,(H,29,30)
|
|||
| InChIKey |
GRQCSOYTLVIPEY-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P2X purinoceptor 7 (P2RX7) | Target Info | Antagonist | [1] |
| Target's Patent Info | P2X purinoceptor 7 (P2RX7) | Target's Patent Info | [1] | |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Reactome | The NLRP3 inflammasome | |||
| WikiPathways | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | P2X7 receptor antagonists: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Mar;27(3):257-267. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.