Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0RG2P
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| Former ID |
DNC012378
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| Drug Name |
SC-50560
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| Synonyms |
SC-50560; CHEMBL85595; SCHEMBL8294789; SCHEMBL6444071; BDBM50046078; L006223; 5-[4''-(3,5-Dibutyl-[1,2,4]triazol-1-ylmethyl)-biphenyl-2-yl]-2H-tetrazole
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| Drug Type |
Small molecular drug
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| Structure |
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Download2D MOL |
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| Formula |
C24H29N7
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| Canonical SMILES |
CCCCC1=NN(C(=N1)CCCC)CC2=CC=C(C=C2)C3=CC=CC=C3C4=NNN=N4
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| InChI |
1S/C24H29N7/c1-3-5-11-22-25-23(12-6-4-2)31(28-22)17-18-13-15-19(16-14-18)20-9-7-8-10-21(20)24-26-29-30-27-24/h7-10,13-16H,3-6,11-12,17H2,1-2H3,(H,26,27,29,30)
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| InChIKey |
LRZYXWIVLLNUPK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Angiotensin II receptor type-2 (AGTR2) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Adrenergic signaling in cardiomyocytes | ||||
| Renin-angiotensin system | ||||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | ACE Inhibitor Pathway | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
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| REF 1 | N1-sterically hindered 2H-imidazol-2-one angiotensin II receptor antagonists: The conversion of surmountable antagonists to insurmountable antagonists, Bioorg. Med. Chem. Lett. 3(6):1055-1060 (1993). | |||
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