Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0RA0P
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| Former ID |
DNC012954
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| Drug Name |
2-amino-2-(thiophen-2-yl)acetic acid
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| Synonyms |
21124-40-3; AMINO-THIOPHEN-2-YL-ACETIC ACID; 2-amino-2-(thiophen-2-yl)acetic acid; Amino(2-thienyl)acetic acid; DL-alpha-Amino-2-thiopheneacetic acid; 2-(2-thienyl)glycine; 4052-59-9; 2-amino-2-(2-thienyl)acetic acid; CHEMBL382570; amino(thiophen-2-yl)acetic acid; 2-Thiopheneacetic acid, alpha-amino-, (-)-; XLMSKXASROPJNG-UHFFFAOYSA-N; (-)-2-Thienylglycine; EINECS 223-758-6; ACMC-20altb; (-)-alpha-Amino-2-thiopheneacetic acid; alpha-(2-Thienyl)glycine; DL-2-(2-Thienyl)glycine; AC1Q5S3H; 2-(Thiophen-2-yl)glycine; AC1L3HV3
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H7NO2S
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| Canonical SMILES |
C1=CSC(=C1)C(C(=O)O)N
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| InChI |
1S/C6H7NO2S/c7-5(6(8)9)4-2-1-3-10-4/h1-3,5H,7H2,(H,8,9)
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| InChIKey |
XLMSKXASROPJNG-UHFFFAOYSA-N
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| CAS Number |
CAS 21124-40-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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