Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R7GH
|
|||
| Former ID |
DIB009208
|
|||
| Drug Name |
CS-526
|
|||
| Synonyms |
AKU-517; R-105266
Click to Show/Hide
|
|||
| Indication | Gastroesophageal reflux disease [ICD-11: DA22.Z] | Discontinued in Phase 1 | [1] | |
| Company |
Sankyo Co Ltd
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C20H22FN3O
|
|||
| Canonical SMILES |
CC1CC1CN2C(=C(C3=CN=NC(=C32)OCC4=CC=C(C=C4)F)C)C
|
|||
| InChI |
1S/C20H22FN3O/c1-12-8-16(12)10-24-14(3)13(2)18-9-22-23-20(19(18)24)25-11-15-4-6-17(21)7-5-15/h4-7,9,12,16H,8,10-11H2,1-3H3/t12-,16+/m0/s1
|
|||
| InChIKey |
NXPLYKRKIFPEOA-BLLLJJGKSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gastric H(+)/K(+) ATPase (Proton pump) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015294) | |||
| REF 2 | Pharmacological profile of novel acid pump antagonist 7-(4-fluorobenzyloxy)-2,3-dimethyl-1-{[(1S,2S)-2-methyl cyclopropyl]methyl}-1H-pyrrolo[2,3-d]... J Pharmacol Exp Ther. 2007 Oct;323(1):308-17. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.