Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R6UV
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| Former ID |
DIB018013
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| Drug Name |
BMS-690514
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| Synonyms |
BMS 690514; BMS690514
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| Drug Type |
Small molecular drug
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| Indication | Chronic pain [ICD-11: MG30; ICD-10: R52.1, R52.2; ICD-9: 338.2, 780] | Phase 2 | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C19H24N6O2
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| Canonical SMILES |
COC1=CC=CC(=C1)NC2=NC=NN3C2=C(C=C3)CN4CCC(C(C4)O)N
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| InChI |
1S/C19H24N6O2/c1-27-15-4-2-3-14(9-15)23-19-18-13(5-8-25(18)22-12-21-19)10-24-7-6-16(20)17(26)11-24/h2-5,8-9,12,16-17,26H,6-7,10-11,20H2,1H3,(H,21,22,23)/t16-,17-/m1/s1
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| InChIKey |
CSGQVNMSRKWUSH-IAGOWNOFSA-N
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| CAS Number |
CAS 859853-30-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
16440760, 23508405, 24419214, 44390420, 56311932, 80481817, 124976959, 126731251, 131549339, 136368033, 136368271, 139411627, 144115737, 152088812, 152258179, 152344096, 160647015, 162011878, 162029688, 163642743, 164042004, 164178266, 174539900, 185997054, 188937099, 198989201, 223366208, 223683351, 227452231, 246525206, 251963024, 251970977, 252154827, 252215017, 252462431
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib. Cancer Res. 2007 Jul 1;67(13):6253-62. | |||
| REF 2 | Preclinical pharmacokinetics and in vitro metabolism of BMS-690514, a potent inhibitor of EGFR and VEGFR2. J Pharm Sci. 2010 Aug;99(8):3579-93. | |||
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