Drug Information
Drug General Information | Top | |||
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Drug ID |
D0R5QF
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Former ID |
DIB018868
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Drug Name |
AR231453
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Synonyms |
AR-231,453; AR 231453; AR-231453
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C21H24FN7O5S
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Canonical SMILES |
CC(C)C1=NOC(=N1)C2CCN(CC2)C3=NC=NC(=C3[N+](=O)[O-])NC4=C(C=C(C=C4)S(=O)(=O)C)F
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InChI |
1S/C21H24FN7O5S/c1-12(2)18-26-21(34-27-18)13-6-8-28(9-7-13)20-17(29(30)31)19(23-11-24-20)25-16-5-4-14(10-15(16)22)35(3,32)33/h4-5,10-13H,6-9H2,1-3H3,(H,23,24,25)
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InChIKey |
DGBKNTVAKIFYNU-UHFFFAOYSA-N
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CAS Number |
CAS 733750-99-7
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Glucose-dependent insulinotropic receptor (GPR119) | Target Info | Agonist | [2] |
KEGG Pathway | cAMP signaling pathway | |||
Insulin secretion | ||||
WikiPathways | Incretin Synthesis, Secretion, and Inactivation |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5653). | |||
REF 2 | A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. Endocrinology. 2007 Jun;148(6):2601-9. |
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