Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R3MT
|
|||
| Former ID |
DIB003896
|
|||
| Drug Name |
Acadesine
|
|||
| Synonyms |
AICAR; Acadra; ADV-P1; ATH-001; Acadesine (intravenous formulation, leukemia); Acadesine (intravenous formulation, leukemia), Advanced In Vitro Cell Technologies
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Diabetic complication [ICD-11: 5A2Y; ICD-9: 253.5, 588.1] | Phase 3 | [1], [2] | |
| Company |
Schering-Plough
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C9H14N4O5
|
|||
| Canonical SMILES |
C1=NC(=C(N1C2C(C(C(O2)CO)O)O)N)C(=O)N
|
|||
| InChI |
1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
|
|||
| InChIKey |
RTRQQBHATOEIAF-UUOKFMHZSA-N
|
|||
| CAS Number |
CAS 2627-69-2
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
8163117, 14774569, 14847938, 17396905, 24715152, 26758179, 29217492, 29285249, 48018877, 57329792, 74850498, 85247950, 89113390, 104253388, 104342656, 104548352, 118046859, 121379620, 124757506, 124893186, 124971563, 125164310, 126671490, 129180315, 129951236, 131477474, 134222485, 134982255, 136349962, 137100921, 137260954, 137673016, 144205104, 162011958, 162037727, 162171410, 163391816, 163688649, 163843374, 164175269, 165245652, 170465608, 172097137, 175426912, 176484784, 178101825, 179150239, 184565448, 198939288, 223438380
|
|||
| ChEBI ID |
CHEBI:28498
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5133). | |||
| REF 2 | Acadesine, an adenosine-regulating agent with the potential for widespread indications. Expert Opin Pharmacother. 2008 Aug;9(12):2137-44. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.