Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D0R2QV
|
|||
Drug Name |
PMID25666693-Compound-122
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Cancer related pain [ICD-11: MG30; ICD-10: R52.1, R52.2] | Patented | [1] | |
Inflammatory pain [ICD-11: MG30.42; ICD-10: R52, G89] | Patented | [1] | ||
Neuropathic pain [ICD-11: 8E43.0] | Patented | [1] | ||
Osteoarthritis pain [ICD-11: MG30.31] | Patented | [1] | ||
Company |
PHARMESTE S.R.L. NAPOLETANO, Mauro TREVISANI, Marcello PAVANI, Maria Giovanna FRUTTAROLO, Francesca
|
|||
Structure |
Download2D MOL |
|||
Formula |
C19H19F3N4O3
|
|||
Canonical SMILES |
CN(C)C1=C(C=CC(=C1)C(F)(F)F)CNC(=O)NC2=CC=CC3=C2OCC(=O)N3
|
|||
InChI |
1S/C19H19F3N4O3/c1-26(2)15-8-12(19(20,21)22)7-6-11(15)9-23-18(28)25-14-5-3-4-13-17(14)29-10-16(27)24-13/h3-8H,9-10H2,1-2H3,(H,24,27)(H2,23,25,28)
|
|||
InChIKey |
NEPJFAHBBJEELA-UHFFFAOYSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Antagonist | [1] |
Target's Patent Info | Transient receptor potential cation channel V1 (TRPV1) | Target's Patent Info | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Inflammatory mediator regulation of TRP channels | ||||
NetPath Pathway | IL2 Signaling Pathway | |||
Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
Reactome | TRP channels |
References | Top | |||
---|---|---|---|---|
REF 1 | Transient receptor potential vanilloid type 1 antagonists: a patent review (2011 - 2014).Expert Opin Ther Pat. 2015 Mar;25(3):291-318. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.