Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0R2HF
|
|||
| Former ID |
DNC013517
|
|||
| Drug Name |
6-(2-mercaptoacetamido)-N-phenylhexanamide
|
|||
| Synonyms |
CHEMBL178727; 6-(2-Mercaptoacetylamino)-N-Phenylhexanamide; 824970-14-1; 6-(2-mercaptoacetamido)-N-phenylhexanamide; 4cqf; SCHEMBL5998899; CTK3D8890; DTXSID50465903; ZINC13609328; BDBM50157884; AKOS030603047; N-phenyl-6-[(sulfanylacetyl)amino]hexanamide; N-Phenyl-6-[(mercaptoacetyl)amino]hexanamide; Hexanamide, 6-[(mercaptoacetyl)amino]-N-phenyl-; 6-(2-Mercapto-acetylamino)-hexanoic acid phenylamide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C14H20N2O2S
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)NC(=O)CCCCCNC(=O)CS
|
|||
| InChI |
1S/C14H20N2O2S/c17-13(16-12-7-3-1-4-8-12)9-5-2-6-10-15-14(18)11-19/h1,3-4,7-8,19H,2,5-6,9-11H2,(H,15,18)(H,16,17)
|
|||
| InChIKey |
ICMLRCZXRBTKLJ-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 824970-14-1
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histone deacetylase 8 (HDAC8) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alcoholism | |||
| Viral carcinogenesis | ||||
| Panther Pathway | Wnt signaling pathway | |||
| Pathway Interaction Database | Signaling events mediated by HDAC Class I | |||
| Reactome | NOTCH1 Intracellular Domain Regulates Transcription | |||
| Constitutive Signaling by NOTCH1 PEST Domain Mutants | ||||
| Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants | ||||
| HDACs deacetylate histones | ||||
| WikiPathways | Integrated Pancreatic Cancer Pathway | |||
| Neural Crest Differentiation | ||||
| Cell Cycle | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Histone deacetylase inhibitors: from bench to clinic. J Med Chem. 2008 Mar 27;51(6):1505-29. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.