Drug Information
Drug General Information | Top | |||
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Drug ID |
D0R0YB
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Drug Name |
PMID25522065-Compound-6
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Drug Type |
Small molecular drug
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Company |
ALBANY MOLECULAR RESEARCH, INC
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Structure |
Download2D MOL |
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Formula |
C25H21F3N4O
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Canonical SMILES |
CN1C2=C(C3CCC(C2)N3)C4=C1C=C(C=C4)N5C=CC(=CC5=O)C6=CN=C(C=C6)C(F)(F)F
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InChI |
1S/C25H21F3N4O/c1-31-20-12-17(4-5-18(20)24-19-6-3-16(30-19)11-21(24)31)32-9-8-14(10-23(32)33)15-2-7-22(29-13-15)25(26,27)28/h2,4-5,7-10,12-13,16,19,30H,3,6,11H2,1H3
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InChIKey |
NAYVWRUHNOMLBF-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Reactome | Peptide ligand-binding receptors | |||
G alpha (q) signalling events | ||||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
Gastrin-CREB signalling pathway via PKC and MAPK | ||||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. |
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