Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0QM0N
|
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| Former ID |
DIB010771
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| Drug Name |
BILD-733
|
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| Drug Type |
Small molecular drug
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| Indication | Herpes simplex virus infection [ICD-11: 1F00; ICD-10: B00; ICD-9: 54] | Terminated | [1] | |
| Company |
Boehringer Ingelheim Corp
|
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| Structure |
 |
Download2D MOL |
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| Formula |
C44H70N6O9
|
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| Canonical SMILES |
CC(C)C(C(=O)NC(C(=O)NC(CC(=O)N1CCCC1)C(=O)NC(C(=O)NC(CC(C)(C)C)CO)C2(CCCC2)C(=O)O)C(C)(C)C)N(C)C(=O)CCC3=CC=CC=C3
|
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| InChI |
1S/C44H70N6O9/c1-28(2)34(49(9)32(52)20-19-29-17-11-10-12-18-29)38(55)47-35(43(6,7)8)39(56)46-31(25-33(53)50-23-15-16-24-50)37(54)48-36(44(41(58)59)21-13-14-22-44)40(57)45-30(27-51)26-42(3,4)5/h10-12,17-18,28,30-31,34-36,51H,13-16,19-27H2,1-9H3,(H,45,57)(H,46,56)(H,47,55)(H,48,54)(H,58,59)/t30?,31-,34-,35+,36+/m0/s1
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| InChIKey |
KEQHTXSUCBEFIM-GSKLOGINSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Herpes simplex virus Ribonucleoside-diphosphate reductase (HSV RIR1) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004139) | |||
| REF 2 | Resistance of herpes simplex virus type 1 to peptidomimetic ribonucleotide reductase inhibitors: selection and characterization of mutant isolates. J Virol. 1996 Feb;70(2):787-93. | |||
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