Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0Q8ZX
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| Former ID |
DAP001234
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| Drug Name |
Benzocaine
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| Synonyms |
Aethoform; Americaine; Anaesthesin; Anaesthesinum; Anaesthin; Anestezin; Anesthesin; Anesthesine; Anesthone; Bensokain; Benzocaina; Benzocainum; Chloraseptic; Dermoplast; Ethoform; Ethoforme; Hurricaine; Identhesin; Keloform; Norcain; Norcaine; Norcainum; Orthesin; Otocain; Outgro; Parathesin; Parathesine; Solarcaine; Topcaine; Aethylium paraminobenzoicum; Amben ethyl ester; Anestezin [Russian]; Baby Anbesol; Benzocaine Acetate; Benzocaine Formate; Benzocaine Hydrobromide; Benzocaine Hydrochloride; Benzocaine Methanesulfonate; Ethyl PABA; Ethyl aminobenzoate; Ethylis aminobenzoas; Solu H; Acetate, Benzocaine; Anaesthan-syngala; Auralgan (TN); Benzocaina [INN-Spanish]; Benzocaine [INN:BAN]; Benzocainum [INN-Latin]; Ethyl 4-aminobenzoate; Ethyl 4-aminobenzoate hydrochloride; Ethyl aminobenzoate (JP15); Ethyl aminobenzoate (VAN); Ethyl p-aminobenzoate; Ethyl p-aminophenylcarboxylate; Ethylaminobenzoate-4; Ethylesterkyseliny p-aminobenzoove; Ethylester kyseliny p-aminobenzoove [Czech]; Formate, Benzocaine; Hydrobromide, Benzocaine; Hydrochloride, Benzocaine; Methanesulfonate, Benzocaine; Ora-jel; P-Aminobenzoic acid ethyl ester; P-Aminobenzoic ethyl ester; P-Carbethoxyaniline; P-Ethoxycarboxylic aniline; Parathesin (TN); AE-562/40377256; Benzocaine (USP/INN); ETHYL-P-AMINOBENZOATE; P-(Ethoxycarbonyl)aniline;P-Aminobenzoic acid, ethyl ester; Benzoic acid, amino-, ethyl ester; H-4-abz-oet; Benzoic acid, 4-amino-, ethyl ester; Benzoic acid, p-amino-, ethyl ester; Benzoic acid, 4-amino-, ethyl ester, hydrochloride; 112909_ALDRICH; 112909_SIAL; 4 Aminobenzoic Acid Ethyl Ester; 4-(Ethoxycarbonyl)aniline; 4-Aminobenzoic acid ethyl ester; 4-Aminobenzoic acid, ethyl ester; 4-Carbethoxyaniline; 4-amino-benzoic acid ethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1] | |
| Therapeutic Class |
Anesthetics
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| Company |
Wyeth Pharmaceuticals
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| Structure |
 |
Download2D MOL |
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| Formula |
C9H11NO2
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| Canonical SMILES |
CCOC(=O)C1=CC=C(C=C1)N
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| InChI |
1S/C9H11NO2/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6H,2,10H2,1H3
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| InChIKey |
BLFLLBZGZJTVJG-UHFFFAOYSA-N
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| CAS Number |
CAS 94-09-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9730, 70931, 96357, 3135295, 4572784, 7847618, 7978768, 8149216, 8151565, 10321900, 10538447, 11112244, 11336107, 11361346, 11362888, 11365450, 11368012, 11371508, 11373797, 11376174, 11462318, 11466740, 11467860, 11483870, 11486580, 11487933, 11490130, 11492064, 11493888, 15219432, 24845986, 24847117, 24894416, 26611622, 26679336, 26747880, 26747881, 36521256, 39774060, 46303101, 46508891, 47216843, 47291205, 47440345, 47515379, 47662359, 47662360, 47736562, 47736563, 48259318
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| ChEBI ID |
CHEBI:116735
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| ADReCS Drug ID | BADD_D00237 ; BADD_D00238 | |||
| SuperDrug ATC ID |
C05AD03; D04AB04; N01BA05; R02AD01
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| SuperDrug CAS ID |
cas=000094097
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Blocker | [2] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
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| REF 1 | Double-blind, randomized, placebo-controlled clinical trials with non-prescription medications for the treatment of obesity. Obes Res. 1999 Jul;7(4):370-8. | |||
| REF 2 | Electrostatic contributions of aromatic residues in the local anesthetic receptor of voltage-gated sodium channels. Circ Res. 2008 Jan 4;102(1):86-94. | |||
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