Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0Q7ZG
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| Former ID |
DAP000513
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| Drug Name |
Proparacaine
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| Synonyms |
Alcaine; Diocaine; Kainair; Ophthaine; Ophthetic; Paracaine; Prossimetacaina; Proximetacaina; Proximetacainum; Proxymetacaine; Proxymetacainum; Prossimetacaina [DCIT]; Proxymetacaine Hcl; Ak-taine; Alcaine (TN); Ocu-Caine; Proximetacaina [INN-Spanish]; Proxymetacaine (INN); Proxymetacaine [INN:BAN]; Proxymetacainum [INN-Latin]; Spectro-Caine; Ak-Taine (TN); Beta-(Diethylamino)ethyl 4-n-propoxybenzoate; BENZOIC ACID, 3-AMINO-4-PROPOXY-, 2-(DIETHYLAMINO)ETHYL ESTER; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate; 2-diethylaminoethyl 3-amino-4-propoxybenzoate; 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-9: 338] | Approved | [1], [2] | |
| Therapeutic Class |
Anesthetics
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| Structure |
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Download2D MOL |
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| Formula |
C16H26N2O3
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| Canonical SMILES |
CCCOC1=C(C=C(C=C1)C(=O)OCCN(CC)CC)N
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| InChI |
1S/C16H26N2O3/c1-4-10-20-15-8-7-13(12-14(15)17)16(19)21-11-9-18(5-2)6-3/h7-8,12H,4-6,9-11,17H2,1-3H3
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| InChIKey |
KCLANYCVBBTKTO-UHFFFAOYSA-N
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| CAS Number |
CAS 499-67-2
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9587, 5371486, 7980413, 8153042, 11112907, 11466987, 11468107, 11486843, 14751470, 29224013, 46507960, 47736674, 47810944, 47885584, 47885585, 49699025, 49885953, 50100537, 50672884, 57322536, 85787393, 92712547, 96025134, 103358193, 104307827, 117714299, 118693180, 123081056, 124882712, 126408033, 126630073, 126731215, 128362287, 131740431, 134223566, 134337806, 134977784, 137003779, 143441499, 144043757, 160964149, 163189882, 164788550, 164832608, 166231861, 174006303, 175266685, 178103857, 179225201, 223364977
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| ChEBI ID |
CHEBI:8485
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| ADReCS Drug ID | BADD_D01862 ; BADD_D01863 | |||
| SuperDrug ATC ID |
S01HA04
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| SuperDrug CAS ID |
cas=000499672
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Modulator | [3] |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7283). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 040074. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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